Gene expression microarray data generator


Guan-Hua Huang
2009-11-20  12:30 - 14:00
Room 302, Freshman Classroom Building

Microarray expression analysis has become one of the most widely used functional genomics tools. Since that, many analytical methods have been proposed. It is desirable to develop realistic models that can be applied in simulating expression values of each gene, and can then be used to assess the analysis methods and testing approaches. We download publicly available raw data of the Affymetrix HG-U133A platform for varied tissues, and then, for each gene, the empirical expression intensity distribution is determined. In this talk, I will provide a process for simulating expression values, using these obtained empirical expression intensity distributions.